Hello on behalf of CORONARY CONNECT my name is Jan Přeček. I'm a cardiologist from the University Hospital Olomouc in the Czech Republic.
I'd like to talk about safety of low levels of LDL cholesterol (LDL-C).

LDL-C as a Risk Factor
Elevated LDL-C is a clearly established major risk factor for the development of atherosclerotic cardiovascular disease.
Risk reduction of atherosclerotic cardiovascular disease is proportional to the absolute and relative LDL-C reduction achieved.
In other words, there seems to be no LDL-C threshold, below which no further atherosclerotic cardiovascular disease prevention can be achieved.